Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2936755 | International Journal of Cardiology | 2006 | 6 Pages |
Abstract
Big endothelin-1 is correlated with the coronary artery stiffness. The effect of endogenous endothelin-1 on coronary artery stiffness is impaired in type 2 diabetes mellitus. This may have important therapeutic implications with respect to the introduction of endothelin receptor antagonists as cardiovascular therapeutic agents.
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Authors
Zenon S. Kyriakides, Dimitrios Th. Kremastinos, Athanasios E. Raptis, Neil Johnston, Sotirios A. Raptis, David J. Webb, Stamatis Kyrzopoulos, Eftichia Sbarouni,