| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2956399 | Journal of the American Society of Hypertension | 2015 | 6 Pages |
•Intradialytic hypotension (IDH) episodes were present in 30.7% of all 774 treatments and 93% of 43 patients.•With increase in the dry weight, the average number of IDH episodes decreased 2.5%.•Patients with hypertension can have up to 2.4 times more IDH episodes on average.•Diabetic patients had on average 1.75 times more IDH events that nondiabetic ones.•Phosphorus level increase was associated with a maximum 50% rise in IDH episodes.
Symptomatic intradialytic hypotension (IDH) continues to be an important complication of hemodialysis treatment. There is some evidence that besides an IDH episode, repeated episodes could represent an even more important independent risk factor for mortality in hemodialysis patients. A retrospective cross-sectional study was performed to study 18 dialysis treatments in 43 patients during 6 weeks. Relationships of IDH episodes with baseline variables were examined using a Poisson regression model (generalized linear model). IDH was frequent (93% of patients) and highly variable by patient (0%–100%). Multivariate analysis showed that patients who experienced frequent hypotensive episodes had a lower dry weight (90% confidence interval [CI]: 0.95–0.99), higher phosphorus levels (90% CI: 1.07–1.47), greater prevalence of diabetes mellitus (90% CI: 1.11–2.71), and hypertension (90% CI: 1.04–2.45). Dry weight, hypertension, and phosphorus levels are modifiable risk factors to possibly reduce the rate of IDH episodes. The potential protective role of phosphorus warrants further investigation.
