Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2966242 | Journal of Clinical Lipidology | 2012 | 10 Pages |
Abstract
Plasma levels of high-density lipoprotein (HDL) are strongly and inversely correlated with atherosclerotic cardiovascular diseases. However, it is becoming clear that a functional HDL is a more desirable target than simply increasing HDL-cholesterol levels. The best known antiatherogenic function of HDL particles relates to their ability to promote reverse cholesterol transport from peripheral cells. However, HDL also possesses antioxidant, anti-inflammatory, and antithrombotic effects. This review focuses on the state of knowledge regarding assays of HDL heterogeneity and function and their relationship to cardiovascular diseases.
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Authors
Hicham Berrougui, Claudia N. Momo, Abdelouahed Khalil,