Article ID Journal Published Year Pages File Type
2969670 The Journal of Heart and Lung Transplantation 2016 32 Pages PDF
Abstract
In this post-infarct heart failure model, either hESC-Pg or their secreted EV enhance recovery of cardiac function and similarly affect cardiac gene expression patterns that could be related to this recovery. Although the mechanisms by which EV improve cardiac function remain to be determined, these results support the idea that a paracrine mechanism is sufficient to effect functional recovery in cell-based therapies for post-infarction-related chronic heart failure.
Related Topics
Health Sciences Medicine and Dentistry Cardiology and Cardiovascular Medicine
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