Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2969906 | The Journal of Heart and Lung Transplantation | 2014 | 26 Pages |
Abstract
In children, including HTx patients, CD21-expressing B-cells show a trend to increase with age, corresponding with improved responsiveness to polysaccharide antigens. This does not differ in patients with ABOi grafts developing tolerance to donor ABO antigens. C3d levels are not age-dependent, but reduced C3d levels after ABOi HTx suggest altered complement metabolism contributing to ABO tolerance.
Related Topics
Health Sciences
Medicine and Dentistry
Cardiology and Cardiovascular Medicine
Authors
Simon MD, Lauren A. BSc, Ingrid M. RN, Kim MSc, Ivan M. MD, David B. MD, Lori J. MD, DPhil,