| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2970009 | The Journal of Heart and Lung Transplantation | 2015 | 8 Pages |
Abstract
By interacting with NO-unresponsive sGC, cinaciguat enhances the protective effects of the NO/cGMP pathway at different steps of signal transduction after global myocardial ischemia/reperfusion. Its clinical use as pre-conditioning agent could be a novel approach in cardiac surgery.
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Authors
Sivakkanan MD, Sevil PhD, Tamás MD, PhD, Shiliang MD, Beatrice Mikles, EnikÅ MD, Kristóf MD, PhD, Matthias MD, Gábor MD, PhD,