Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2970155 | The Journal of Heart and Lung Transplantation | 2015 | 12 Pages |
Abstract
The cellular composition of the ELS differs from the cellular infiltrate in CAV intimal lesions. The presence of memory B lymphocytes and plasma producing IgM and IgG cells suggests that ELS are related to local antibody production, potentially contributing to antibody-mediated CAV. ELS associated with coronary vessels containing CAV show features of underdeveloped TLOs; classic TLOs may not develop due to patient immunosuppression.
Related Topics
Health Sciences
Medicine and Dentistry
Cardiology and Cardiovascular Medicine
Authors
Manon M.H. MSc, Alison J. PhD, Aryan MD, PhD, Rianne MSc, Hannah BSc, Johanna M.T. BSc, Erica BSc, Ton BSc, Nicolaas de MD, PhD, Roel A. PhD, Timothy D.G. PhD,