Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2970354 | The Journal of Heart and Lung Transplantation | 2013 | 10 Pages |
Abstract
This is the first example of antibody-mediated imaging of chronic cardiac rejection. The findings pave the way to immuno-positron emission tomography (immuno-PET) imaging of this clinical condition in patients using the human F8 antibody labeled with a suitable radionuclide (e.g., iodine-124). Furthermore, it would be conceivable to use the F8 antibody as a delivery vehicle to assess experimentally whether a bioactive payload (e.g., drug or cytokine) may be able to reduce disease progression.
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Authors
Marcus MD, Ingrid MD, Katja PhD, Susanne PhD, Petra MD, Iver MD, Christian MD, Jan MD, Hans R. MD, Hartwig MD, Dario PhD, Alexander PhD, André MD,