| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2971737 | The Journal of Heart and Lung Transplantation | 2009 | 8 Pages |
Abstract
This study demonstrated that the administration of the PPARa ligand, WY14643, ameliorates acute lung allograft rejection in rats. Treatment with WY14643 reduced histopathologic scores, prolonged graft survival, and up-regulated the expression of anti-inflammatory cytokine IL-4, IL-10, and TGFβ mRNA compared with the control.
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Authors
Jun MD, Takeshi MD, Akinori MD, Shinichi MD, Takao MD, Masafumi MD, Toshihiro MD, Hirotomo MD, Masahide MD, Takayuki MD,