Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2971815 | The Journal of Heart and Lung Transplantation | 2010 | 9 Pages |
Abstract
The presence of DSA in AMR and CAV is significantly associated with development of Abs to MYO and VIM in post-HTx patients. Induction of high CD4+ Th cells specific to cardiac self-antigens that secrete predominantly IL-5 and IL-17 plays a significant role in the development of Abs to self-antigens leading to AMR and CAV, respectively.
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Authors
Dilip S. MD, Haseeb MD, Venkataswarup MD, PhD, Chiraag BS, Donna BA, Gregory A. MD, Nader MD, Thalachallour PhD,