Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2972008 | The Journal of Heart and Lung Transplantation | 2009 | 7 Pages |
Abstract
In end-stage congestive cardiac failure, intravenous milrinone and sildenafil both cause similar reductions in systemic and pulmonary vascular resistance; however, milrinone has more cardiac selective effects on left ventricular filling and heart rate. Both agents appear to have a suitable hemodynamic profile for testing of reversibility of secondary pulmonary hypertension in congestive cardiac failure. Larger studies are needed to confirm these results.
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Authors
Phil MRCS, Gareth FRCP, John H. FRCS, Guy A. MD, FRCPI,