Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2972430 | The Journal of Heart and Lung Transplantation | 2008 | 10 Pages |
Abstract
Our data demonstrate that supCD28 MAb targets expansion of nTreg cells in vivo and maintains and enhances their regulatory functions, which represents a major advance toward the therapeutic use of polyclonally activated Treg cells as cellular therapy for treatment of allograft rejection.
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Authors
Yusuke PhD, Masayuki PhD, Takatoshi BS, Haruhito MD, PhD, Hiromitsu MD, Yoshitaka MD, PhD, Shiro MD, PhD, Thomas MD, PhD, Ryo MD, PhD, Xiao-Kang MD, PhD,