Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2972733 | The Journal of Heart and Lung Transplantation | 2007 | 7 Pages |
Abstract
Our experience and review of the literature highlights the importance of early diagnosis and differentiation from Aspergillus, since Scedosporium is inherently resistant to amphotericin B. Effective therapeutic approaches being explored include combinations of anti-fungals, because even the newer triazoles have a 50% response rate in clinical studies. Surgical débridement and immune recovery are associated with improved prognosis, favoring the use of agents that expedite immune reconstitution in these patients. Close monitoring of clinical improvement and frequent reevaluation of treatment is essential.
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Authors
Hina MD, Robin K. MD, Omar A. MD, Geraldine PhD, Atul C. MD, Paola MD, Marie DO, MPH,