| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2972755 | The Journal of Heart and Lung Transplantation | 2008 | 7 Pages |
Abstract
ECP extends graft survival even in fully histoincompatible strain combinations with no immunosuppression. It increases the frequency of FoxP3+CD4+CD25+ splenic T cells, and its effects can be transferred to untreated recipients using minimal numbers of CD4+CD25+ T cells, indicating that CD4+CD25+ T cells may play a key role in the immunomodulatory effects of ECP.
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Authors
James F. PhD, Christie W. MD, Wing Hong MD, James K. MD,