Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2977305 | Journal of Nuclear Cardiology | 2007 | 12 Pages |
Abstract
In HCM attributable to the Asp175Asn mutation in the α-tropomyosin gene, myocardial oxidative metabolism and FFA metabolism are increased and inversely related to LV hypertrophy at both the whole heart and regional level. Increased metabolism and efficiency characterize patients with mild myocardial hypertrophy. These hypermetabolic alterations regress with advanced hypertrophy.
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Authors
Helena MD, Johanna MD, PhD, Jyri MD, PhD, Pertti MD, PhD, Päivi MSc, Keijo MD, PhD, Tapio MSc, Petri MD, Kira Q. MSc, PhD, Jarna MSc, Pirjo MD, PhD, Markku MD, PhD, Juhani MD, PhD,