Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2979280 | The Journal of Thoracic and Cardiovascular Surgery | 2015 | 13 Pages |
Abstract
The extracellular matrix patch enhanced with controlled release of fibroblast growth factor facilitated in situ constructive repopulation of the host cells, including cardiomyocyte and functional regeneration, increased regional contractility and tissue perfusion, and positive electrical activity in a porcine preparation.
Keywords
ECMModified Look-Locker inversion recoverySENCMOLLISVRCMRROIECVvWFFGF-2LGElate gadolinium enhancementsurgical ventricular restorationCardiovascular magnetic resonance imagingMyocardial repaircardiovascular magnetic resonanceDrug delivery systemVon Willebrand factorGrowth factorbasic fibroblast growth factorextracellular volume fractionExtracellular matrixregion-of-interestTissue engineering
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Authors
Akiko MD, PhD, Keigo PhD, Amit R. MD, Yasuhiko PhD, DMedSci, DPharm, Martin C. DO, Mahesh P. PhD, Takeyoshi MD, PhD,