| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2979489 | The Journal of Thoracic and Cardiovascular Surgery | 2015 | 12 Pages |
Abstract
Expression of hHGF and hMCP-1 were found in rabbit lung after gene transfection via an airway approach. By increasing the pulmonary microvascular density and promoting arterializations, sequential and timely hHGF/hMCP-1 transfection ameliorates the shunt flow-induced pulmonary artery hypertension.
Keywords
PAHSMCmRNAeGFPhHGFVECHGFMCP-1AdenovirusAngiogenesissmooth muscle actinSMAmessenger ribonucleic acidvascular endothelial cellSmooth muscle cellHepatocyte growth factorHepatocyte growth factor (HGF)human hepatocyte growth factorPulmonary arterial hypertensionplaque-forming unitsMonocyte chemotactic protein-1enhanced green fluorescent proteinpfu
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Authors
Yiqian MD, Fang MD, Xiaoyu MD, Yue MD, Junjie MD, PhD, Peng MD, Wei MD,