Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2979962 | The Journal of Thoracic and Cardiovascular Surgery | 2015 | 6 Pages |
Abstract
Device type was not a factor in patient sensitization after implantation. However, VAD patients required pre-existing sensitization before implantation to produce antibodies during their treatment interval, whereas more than two thirds of BIVAD patients developed de novo antibodies. These data suggest that the mechanism of sensitization between VAD and BIVAD patients may differ, and further mechanistic studies into the impact of device types on patient sensitization are warranted.
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Authors
Murray H. MD, Jennifer Q. PhD, Joanna M. MD, PhD, Martin MD, David W. PhD, Carolyn A. Krystal, Hillel MD, Abbas MD, Mario C. MD, Richard J. MD, Elaine F. PhD,