| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2980930 | The Journal of Thoracic and Cardiovascular Surgery | 2013 | 9 Pages |
Abstract
Administration of carbon monoxide to the deceased donor and non-heart-beating donor lungs reduces ischemia-reperfusion injury in rat lungs transplanted from non-heart-beating donors. Therapy to the deceased donor via the airway may improve post-transplant lung function.
Keywords
iNOS38.1DCDIκBα11.4EVLPTNFEx vivo lung perfusionLTXERKcGMPmRNANF-κBJnkNHBDc-Jun N-terminal kinaseIRIMAPKmessenger RNAIschemia–reperfusion injuryNitrous oxideinterleukininducible nitric oxide synthasePulmonary arterytumor necrosis factornuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alphanuclear factor kappa Bcarbon monoxidecyclic guanosine monophosphatemitogen-activated protein kinaseLung transplantationextracellular signal-regulated kinase
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Authors
Boming MD, PhD, Paul W. PhD, Thomas M. MD, MSc,