Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2981878 | The Journal of Thoracic and Cardiovascular Surgery | 2011 | 10 Pages |
Abstract
This is the first report associating elevated serum UCHL1 with brain injury. The novel neuronal biomarker UCHL1 is increased in serum 8 hours after severe neurologic insult in 2h-HCA animals compared with CPB animals. These results support the potential for use in cardiac surgery patients and form the basis for clinical correlation in humans.
Keywords
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Authors
George J. MD, Timothy J. MD, Kevin K. PhD, Mary Ann PhD, Jeremiah G. MD, Chase W. MHS, Kara A. BS, Eric S. MD, MPH, Mary E. PhD, Charles C. BA, Juan C. MD, Michael V. MD, William A. MD,