Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2981930 | The Journal of Thoracic and Cardiovascular Surgery | 2010 | 13 Pages |
Abstract
Adaptation to global elevation in systemic venous pressure to Fontan levels is complete within 2 weeks. Increased blood volume and reduced heart rate are persistent responses. Increased oxygen extraction and neurohormonal up-regulation are temporary responses that normalize with recovery of cardiac output. With improved physiologic understanding of systemic adaptation to Fontan conversion, approaches to single-ventricle palliation can be more objectively assessed and optimized.
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Authors
Cynthia D. MD, Kimberly BA, Lindsay E. MD, Kelly D. MD, Kenneth DVM, PhD, Mark D. MD,