Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2982013 | The Journal of Thoracic and Cardiovascular Surgery | 2009 | 9 Pages |
Abstract
Local delivery of tannic acid prevents collagen matrix degradation via cross-linking fibrous collagen and inhibiting matrix metalloproteinase activity but does not improve the intrinsic contractile function of myocardium. This treatment may be helpful to attenuate the adverse topographic remodeling after acute myocardial infarction.
Keywords
ECMMMPTIMP-2PBSEDDDMEMESD3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromideDulbecco's modified Eagle MediumMTTMyocardial infarctionSprague-DawleyTannic acidOctLeft ventricularoptimum cutting temperatureExtracellular matrixmatrix metalloproteinasephosphate-buffered saline solutiontissue inhibitor of metalloproteinase-2fractional shortening
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Authors
Hao MD, PhD, Shen-jun MD, De MD, PhD, Ying-jie PhD, Sheng-Shou MD,