| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2983038 | The Journal of Thoracic and Cardiovascular Surgery | 2010 | 12 Pages |
Abstract
The omentum-based cell-supporting patch provided a favorable microenvironment for transplanted mesenchymal stem cell survival, which resulted in favorable ventricular remodeling and restoration of cardiac function in rats with experimental myocardial infarction. Further validation of the technique in human subjects could make mesenchymal stem cell transplantation a viable therapeutic option for patients with cardiac disease.
Keywords
PLGALVFSLVESDCX43LVEDdLVEFMSCDAPISCF4′-6-diamidino-2-phenylindole dihydrochlorideMyocardial infarctioncoronary artery bypass graftingTUNELCABGMesenchymal stem cellVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)Stem Cell Factorleft ventricular end-diastolic diameterleft ventricular end-systolic diameterpolymerase chain reactionPCRleft ventricular ejection fractionconnexin 43left ventricular fractional shortening
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Authors
Qi MD, PhD, Jian-Ye MS, Zhe MD, PhD, Hao MD, PhD, Sheng-Shou MD,