| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2983541 | The Journal of Thoracic and Cardiovascular Surgery | 2008 | 6 Pages |
Abstract
Aprotinin provides direct neuroprotection against glutamatergic excitotoxicity as demonstrated by reduced neuronal death in near-pure neuronal cell culture. Additional studies are needed to evaluate the potential of aprotinin to reduce neurologic injury in patients at high risk of cerebral injury, including those undergoing circulatory arrest.
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Authors
Yusuke MD, Olivier PhD, Toru MD, David PhD, Richard A. MD,