| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2984725 | The Journal of Thoracic and Cardiovascular Surgery | 2010 | 13 Pages |
Abstract
We demonstrated that somatic D310 mutations and increase in the copy number of mitochondrial DNA are of clinical importance in esophageal squamous cell carcinoma. We also propose a model of DNA instability and clonal expansion during the carcinogenesis and progression of esophageal squamous cell carcinoma from the viewpoint of mitochondrial DNA transmission.
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Authors
Chen-Sung MD, Shi-Chuan MD, PhD, Liang-Shun MD, Teh-Ying MD, PhD, Wen-Hu MD, Yu-Chung MD, Yau-Huei PhD,