Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2985189 | The Journal of Thoracic and Cardiovascular Surgery | 2006 | 9 Pages |
Abstract
Our data demonstrate that intravenously infused embryonic stem cell-derived cells homed to the infarcted heart, improved cardiac function, and enhanced regional blood flow at 6 weeks after myocardial infarction. The in vitro migration assay suggested that such a homing mechanism could be associated with locally released cytokines, such as tumor necrosis factor α, that are upregulated in the setting of acute myocardial infarction and heart failure.
Keywords
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Authors
Jiang-Yong MD, Xuling MD, Meixiang MD, PhD, Achim MD, Yu MD, Qingen MD, Emel BS, Jamal S. MD, Peter MD, PhD, James P. MD, PhD,