Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2985307 | The Journal of Thoracic and Cardiovascular Surgery | 2006 | 9 Pages |
Abstract
A pre-emptive omega-3 infusion significantly reduces infarct size through the dual mechanisms of upregulation of heat shock protein 72, a key preconditioning protein, and a dramatic increase in the omega-3 content of myocardial membranes, which appears to facilitate a shift in oxidant ischemia-reperfusion injury. Further study to optimally shorten the pretreatment regimen for this potentially acceptable infusion will now be pursued.
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Authors
J. MB, BCh, BAO, AFRCSI, T.G. MD, A. MSc, D. MCh, FRCSI, J.M. MD, FRCSI,