| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2986177 | The Journal of Thoracic and Cardiovascular Surgery | 2008 | 14 Pages |
Abstract
The dynamic changes in mitochondrial membrane potential during right ventricular hypertrophy are chamber-specific, associated with activation of NFAT, and can be pharmacologically reversed leading to improved contractility. This mitochondrial remodeling might provide a framework for development of novel right ventricle-specific therapies.
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Authors
Jayan MD, Vikram BSc, David Z. BSc, Jason R.B. PhD, Al BSc, David B. MD, Ivan M. MD, Evangelos D. MD,