Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2986347 | The Journal of Thoracic and Cardiovascular Surgery | 2008 | 9 Pages |
Abstract
In this model of pressure overload hypertrophy, intracoronary delivery of mesenchymal stem cells during heart failure was associated with an improvement in hemodynamic performance, maximal exercise tolerance, systemic inflammation, and left ventricular reverse remodeling. This study suggests a potential role of this treatment strategy for the management of hypertrophic heart failure resulting from pressure overload.
Keywords
PBSLVESPLVEDPGFPLVESDMSCLVEDdBrdUbromodeoxyuridineLeft ventricularELISAEnzyme-linked immunosorbent assayMesenchymal stem cellleft ventricular end-systolic pressureleft ventricular end-diastolic pressureleft ventricular end-diastolic diameterleft ventricular end-systolic diameterphosphate-buffered saline solutiongreen fluorescent proteinbrain natriuretic peptide
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Authors
Ezequiel J. MD, Jon MS, Dipin MD, Denise MD, John P. PhD, Steven PhD, Mahender MD,