Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2986514 | The Journal of Thoracic and Cardiovascular Surgery | 2006 | 10 Pages |
Abstract
Our study demonstrates that, in acute single-ventricle physiology with aortopulmonary shunt, myocardial blood flow is maintained by lower coronary perfusion pressure. Further, single-ventricle physiology results in less favorable myocardial oxygen supply/demand balance, although normal transmural myocardial blood flow distribution is maintained. Avoidance of diastolic runoff (ventricle-pulmonary conduit) could improve coronary reserve. In our study, moderate afterload augmentation did not induce relative subendocardial malperfusion, nor did it worsen oxygen supply/demand balance.
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Authors
Marco MD, Pierluca MD, Alvaro MD, Steven MD, Amelia Vasquez, Eliot MD,