Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3010232 | Resuscitation | 2009 | 6 Pages |
Abstract
Our results show that CA with consecutive successful CPR leads to a microcirculatory impairment closely resembling experimentally induced sepsis. Intriguingly, despite these similarities, rhAPC had no significant effects on WSR and PE. Our results strongly suggest that further mechanisms such as mast cell activation might play an important role and have therefore to be studied to elucidate the pathophysiology of “postresuscitation disease”.
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Authors
Peter Teschendorf, Stephan A. Padosch, Daniela del Valle y Fuentes, Christoph Peter, André Fuchs, Erik Popp, Fabian Spöhr, Bernd W. Böttiger, Andreas Walther,