| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3026888 | Thrombosis Research | 2016 | 9 Pages |
Abstract
TM exhibits significant binding affinity for complement protein FH and C3b-FH complex and its soluble form is capable at physiologically relevant concentrations of inhibiting complement activation in serum.
Keywords
TAFICH50PPACKEGFNHSIC50DICDIC, Disseminated intravascular coagulationThrombomodulinHemolytic assaySurface plasmon resonanceSPRshort consensus repeatHUSCFDnormal human serumHemolytic uremic syndromeSheaFactor BFactor Hfactor IComplementalternative pathwaylectin pathwayclassical pathwayMACmembrane attack complexSCR
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Authors
M. Heurich, R.J.S. Preston, V.B. O'Donnell, B.P. Morgan, P.W. Collins,