Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3027177 | Thrombosis Research | 2013 | 7 Pages |
Abstract
The immunoglobulin superfamily member EMMPRIN (CD147) plays an important role in a number of organ systems, including the cardiovascular system. Here we review the contemporary understanding of EMMPRIN and EMMPRIN-associated sequelae in the course of atherosclerosis. A significant body of data documents the pivotal role of EMMPRIN in the complex processes of atherogenesis, atheroprogression, and acute atherosclerothrombosis, a role that goes beyond that of a mere marker of inflammation.
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Authors
Nader Joghetaei, Andreas Stein, Robert A. Byrne, Christian Schulz, Lamin King, Andreas E. May, Roland Schmidt,