Article ID Journal Published Year Pages File Type
3029402 Thrombosis Research 2008 10 Pages PDF
Abstract

In the past decade development of aptamer technology is poised into several fields with various clinical applications. With this progress, aptamer based anti-coagulant agents are evolved and continuing their applications with clinical trials. At present several anti-coagulant aptamers are available against different proteins from blood coagulation cascade. In this review, the mechanism and functions of anti-coagulant aptamers, as an alternate candidate to other available anti-coagulant agents are discussed.

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