Evaluation of a new silica clotting time in the diagnosis of lupus anticoagulants

Article ID	Journal	Published Year	Pages	File Type
3029854	Thrombosis Research	2007	12 Pages	PDF

Abstract

In comparison with PTT-LA as screening test, the SCT screen shows an acceptable sensitivity. However, the HemosILâ¢ SCT assay including the confirmation step, has a much lower sensitivity in the diagnosis of LAC in comparison with the Staclot-LA test. Combining the HemosILâ¢ SCT assay with dRVVT results in a better sensitivity, although lower than the combined aPTT/dRVVT based method as usually performed in our lab.

Keywords

KCT ISTH dRVVT International Society of Thrombosis and Haemostasis normal pooled plasma LAC APL ROC APTT SEC APs ScT Thrombosis seconds ACL activated partial thromboplastin time Antiphospholipid syndrome antiphospholipid anticardiolipin Coefficient of Variation lupus anticoagulants receiver operator curve