Significant relationship between platelet activation and intra-media thickness of the carotid artery in patients with ischemic cerebrovascular disease

Platelet activation markers were increased in patients with ischemic CVD compared with controls. A significant relationship was found between increased CD62-P-positive platelets and carotid artery abnormalities in both controls and ischemic CVD patients, suggesting that platelet activation may be a potential marker for atherosclerosis.