| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3034447 | Autonomic Neuroscience | 2016 | 9 Pages |
Abstract
These results suggest that ATP released from sympathetic nerves acts on P2X1 purinoceptors located on prostate smooth muscle to evoke EJPs, while pre-junctional α2-adrenergic and adenosine A2 receptors may play a role in preventing excessive transmitter release. Age-related up-regulation of enzymatic ATP breakdown may be a compensatory mechanism for the enhanced purinergic transmission which would cause hypercontractility arising from increased ATP release in older animals.
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Authors
Michelle Lam, Retsu Mitsui, Hikaru Hashitani,