Article ID Journal Published Year Pages File Type
3037134 Brain and Development 2014 5 Pages PDF
Abstract

A 5-year-old girl exhibited daily episodes of repetitive blinking lasting 5–10 s. Electroencephalography (EEG) revealed marked photoparoxysmal responses (PPR) at 3–20 Hz of photic stimulation and diffuse spike-wave bursts during sleep. A 24-h video EEG identified 11 episodes of repetitive blinking, 3 of which resulted in widespread spike-wave discharges. These suggested that the behavior of the patient represented self-induction of PPR. Valproate sodium was ineffective in decreasing PPR, as revealed by EEG, and the frequency of blinking episodes, but clonazepam attenuated PPR and significantly decreased the blinking behavior.

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Life Sciences Neuroscience Developmental Neuroscience
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