Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3038096 | Brain and Development | 2008 | 4 Pages |
Abstract
We describe a girl with sepsis-associated encephalopathy complicating biliary atresia. At 4 months of age, decreased consciousness and repetitive seizures of the left upper and lower extremities occurred in association with fever. Pseudomonas aeruginosa was cultured from blood, while bacterial culture was negative and cell counts were normal in cerebrospinal fluid. The interleukin-6 level in the cerebrospinal fluid was markedly elevated. MRI revealed unilateral subcortical white matter lesions in the right hemisphere. She was diagnosed as having sepsis-associated encephalopathy and was treated with dexamethasone and midazolam. She achieved normal psychomotor development until the last follow-up at 19 months of age, whereas mild atrophic changes were observed in the right hemisphere.
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Authors
Shinpei Abe, Akihisa Okumura, Tohru Fujii, Tomonosuke Someya, Rieko Tadokoro, Yasuhiro Arai, Tomoyuki Nakazawa, Yuichiro Yamashiro,