| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3038401 | Brain and Development | 2008 | 4 Pages |
Abstract
We report the case of a girl with hemimegalencephaly (HME) and Lennox–Gastaut syndrome (LGS) treated by callosotomy at 1 year of age. Over 10 years, her seizure frequency and severity decreased markedly. Hemispherectomy is the main surgical option for HME although HME appears to correlate with a less favorable seizure outcome. However, the clinical presentation of LGS and possible generalized cortical dysplasia, which is indicative of a secondarily generalized epilepsy, might predict a favorable surgical outcome of corpus callosotomy in patients of HME, as in our case.
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Authors
Shang-Yeong Kwan, Hann-Yeh Shyu, Ji-Ho Lin, Tai-Tong Wong, Kai-Ping Chang, Chun-Hing Yiu,