Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3041706 | Clinical Neurology and Neurosurgery | 2008 | 4 Pages |
Abstract
Prefrontal cortex dysfunction has been associated with a series of behavioral symptoms, such as impulsivity and affective instability, which are the defining features of several personality disorders, notably, borderline personality disorder. We report on a 27-year-old patient with schizencephaly in the right frontal lobe (cingulate cortex lesion and secondary orbitofrontal cortex dysfunction) presenting with prominent borderline features and compromise of executive functions, decision-making and attention. We hypothesize that the personality disorder of our patient could be related to cingulate cortex lesion and secondary orbitofrontal cortex dysfunction associated with schizencephaly.
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Authors
Felipe Filardi da Rocha, Leandro Malloy-Diniz, Karla Cristhina Alves de Sousa, Hugo Alejandro Cano Prais, Humberto Correa, Antonio Lucio Teixeira,