| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3043041 | Clinical Neurophysiology | 2013 | 6 Pages |
ObjectiveThe enhancement of blink reflex (BR) excitability was shown in patients with postparalytic facial syndrome (PFS) and essential blepharospasm (EB). We prospectively investigated patients with PFS and EB whether BR alterations demonstrated by trigeminal stimulation will similarly be observed upon auditory stimulation.MethodsFifteen patients with PFS, 15 patients with EB, and 30 healthy volunteers were involved. Electrically stimulated trigeminal BR and auditory BR were studied bilaterally.ResultsThe mean R2 amplitude and duration values were highest in EB patients, being significantly higher than PFS patients (p < 0.05) and control group (p < 0.01). The mean R2 duration in PFS patients were also significantly longer in compared to control group (p = 0.025). EB patients showed a higher mean R (auditory) amplitude and duration than PFS patients (p < 0.05) and controls (p < 0.04). The mean R (auditory) duration was longer on symptomatic side of PFS patients in compared to controls (p = 0.05).ConclusionsWe observed that there is an enhanced excitability of BR circuit in postparalytic facial syndrome and essential blepharospasm, which could be evoked by auditory stimulation in addition to trigeminal stimulation.SignificanceThe enhanced excitability in patients with EB and PFS probably originates from the final common pathway of BR circuit, namely facial motor or premotor neurons.
► We designed a prospective study of trigeminal and auditory blink reflex responses in postparalytic facial syndrome and blepharospasm. ► We observed enchancements in blink reflex circuits in both, probably via peripheral pathways in postparalytic facial syndrome, but via central mechanisms in blepharospasm. ► We also observed that enhanced excitability of blink reflex circuit is evoked by auditory stimulation in addition to trigeminal stimulation.
