Article ID Journal Published Year Pages File Type
3047046 Clinical Neurophysiology 2008 16 Pages PDF
Abstract

ObjectiveThe purpose of the present study was to investigate whether children with reading disabilities (RD) process rise time and pitch changes differently to control children as a function of the interval between two tones.MethodsChildren participated in passive oddball event-related potential (ERP) measurements using paired stimuli. Mismatch negativity (MMN), P3a and late discriminative negativity (LDN) responses to rise time and pitch changes were examined.ResultsControl children produced larger responses than children with RD to pitch change in the P3a component but only when the sounds in the pair were close to each other. Compared to children with RD, MMN was smaller and LDN larger in control children in response to rise time change when the sounds in the pair were further apart. The non-overlap in ERP measures between the groups was 40–50%.ConclusionsProblems in rapid processing of pitch change were reflected in a component associated with attention switching while amplitude envelope processing problems were reflected in components associated with stimulus detection or discrimination.SignificanceChildren with RD process both rise time and pitch changes differently from control children thus providing evidence for the nature of amplitude envelope processing and rapid auditory processing deficits in dyslexia.

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