Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3052130 | Epilepsy Research | 2013 | 8 Pages |
Abstract
SummaryDysfunction of excitatory and inhibitory neurotransmitters or neuromodulators is thought to underlie epileptic symptoms. Taurine, 2-aminoethanesulfonate, is a ubiquitous free amino acid abounding in the brain of humans and most animal species. It hyperpolarizes neurons and inhibits their firing. It may be a participating factor in certain subpopulations of epilepsy patients but its deficiency is not a universal prerequisite for seizures. Here, the participation of taurine in animal seizure models and human epilepsy patients is reviewed.
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Authors
Simo S. Oja, Pirjo Saransaari,