Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3052510 | Epilepsy Research | 2010 | 5 Pages |
Abstract
SummaryWe have experimentally shown that thalidomide has strong anticonvulsant properties. In an open label study, eight male patients with refractory epilepsy received thalidomide at daily-doses of 200 mg during 1 year, frequency of seizures before and during treatment were compared. The mean number of seizures before thalidomide administration was 26 ± 4 per month; it decreased to 7 ± 1 along thalidomide therapy. Our results indicate that thalidomide has strong therapeutic effects in refractory epilepsy.
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Authors
Guadalupe Palencia, Iris E. Martinez-Juarez, Alejandra Calderon, Carol Artigas, Julio Sotelo,