| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3052866 | Epilepsy Research | 2009 | 4 Pages |
Abstract
SummaryAbnormal connectivity might be involved in the pathophysiology of Tuberous Sclerosis Complex (TSC). We used twin-coil Transcranial Magnetic Stimulation protocol to investigate connectivity between posterior parietal cortex (PPC) and motor cortex (M1) in TSC patients. In comparison with healthy subjects and TSC patients treated with antiepileptic drugs, non-medicated TSC patients exhibited abnormal excitability of PPC–M1 connection. Such altered connectivity might play a role in TSC epileptic phenotype.
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Authors
Luigi D’Argenzio, Giacomo Koch, Roberta Bombardieri, Francesco Mori, Romina Moavero, Diego Centonze, Paolo Curatolo,