| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3054459 | European Journal of Paediatric Neurology | 2011 | 4 Pages |
Abstract
Leukoencephalopathies have been reported after heroin inhalation or ingestion, and buprenorphine injection, but the physiopathology remains unclear. We report here the first case of leukoencephalopathy caused by buprenorphine ingestion in a 2-year-old child who was admitted for coma and fever. Due to technical problems, the toxicology screen was delayed, and infectious disease was first suspected. A brain MRI found bilateral and symmetric white matter damages in the cerebral hemispheres and the cerebellum. Rapid recovery and positive toxicology screen for buprenorphine on day 4 confirmed the diagnosis of acute intoxication.
Related Topics
Life Sciences
Neuroscience
Developmental Neuroscience
Authors
Blandine Bellot, Fabrice Michel, Laurent Thomachot, Kathia Chaumoitre, Fabrice Battaglia, Pierre Lagier,