| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3054702 | European Journal of Paediatric Neurology | 2007 | 4 Pages |
Abstract
The authors report a pilot open-label two-center therapeutic trial of oxatomide in 14 steroid-naive DMD boys aged 5–10 years. Comparison of linear evolutions between 3 months medication-free lead-in periods and 6 months treatment periods showed no significant differences in quantitative (QMT) and manual (MMT) measurements of muscle strength and timed functional tests. A modest mitigation of strength deterioration over time cannot be excluded.
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Authors
Gunnar M. Buyse, Nathalie Goemans, Erik Henricson, Alejandro Jara, Marleen van den Hauwe, Robert Leshner, Julaine M. Florence, Jill E. Mayhew, Diana M. Escolar,