Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3055925 | Experimental Neurology | 2011 | 12 Pages |
Abstract
⺠The NOP receptor antagonist Compound 24 attenuates parkinsonism in 6-OHDA rats. ⺠Compound 24 affects motor behavior acting on nigral NOP receptor. ⺠Motor effects are consistent with a dual modulation of nigro-thalamic neurons. ⺠Nigral D2/D3 receptors regulate the responsiveness of nigro-thalamic neurons to Compound 24.
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Authors
Mattia Volta, Riccardo Viaro, Claudio Trapella, Matteo Marti, Michele Morari,