Primary epidural liposarcoma of the cervical spine: Technical case report and review of the literature

•Liposarcoma is the most common soft tissue sarcoma in adults.•Primary Liposarcoma of the spine is rare.•We present for the first time a patient with primary liposarcoma of the cervical spine.•We present transmuscular transpedicular navigated screw placement at C3–C7 level.

Liposarcoma is the most common soft tissue sarcoma in adults. These tumors have a high incidence of osseous metastases, with a propensity to the spine; however, primary spinal involvement is very rare. A 56-year-old female patient presented with a 4 month history of cervical pain, including radiation to both upper limbs, without radicular distribution. Magnetic resonance imaging (MRI) showed an epidural lesion with gadolinium enhancement and bilateral extension into the intervertebral neural foramina (C5–C7), with spreading on the right side of the tumor into paravertebral tissue. The histopathological diagnosis was myxoid liposarcoma. To our knowledge it is the first case of primary myxoid liposarcoma of the cervical spine in the literature. Although rare, our case demonstrates that liposarcoma should be considered in the differential diagnosis of cervical tumors.